EPSRC Doctoral Landscape Award Studentship: “Decoding developmental disorders: AI-powered tools for genotype-phenotype predictions”

King’s College London

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Fully funded PhD studentship in the School of Biomedical Engineering & Imaging Sciences to start 1 October 2025

Award details

The overall aim of this PhD project is to understand and predict how genetic mutations disrupt brain development to give rise to range of debilitating neurodevelopmental disorders.

Aims:

  1. Work with our harmonised multi-omic datasets to build AI tools which predict neurodevelopmental disorder phenotype-genotype associations.
  2. Adapt natural language processing tools to extract and summarise the MRI imaging findings associated with individuals across the range of genetic neurodevelopmental disorders.
  3. Build generative AI models to predict phenotypic profiles that can be used to aid clinical decision making and variant interpretation

They will work with the multidisciplinary IMAGINE lab, collaborating with computer scientists and engineers in the Departments of Biomedical Computing and Early Life Imaging within the School of Biomedical Engineering and Imaging Sciences, KCL, and clinicians at specialist children’s hospitals Great Ormond Street Hospital and Evelina.

The student will have the opportunity to develop skills and expertise in neurodevelopment, machine learning, genetics and clinical translation.

Please visit the studentship webpage for further details and to apply.

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