MSc by Research: Development of tools suited for the in vivo identification and study of protein complexes in Phytophthora capsici, required for infection

University of Dundee

Broad host range pathogens, such as the oomycete pathogen Phytophthora capsici, can cause significant disease on a wide range of plants. We have uncovered exciting new evidence demonstrating that P. capsici regulates the expression of its gene complement by sensing its host environment. In order to study the role of P. capsici proteins in dynamic host sensing however, there is a great need for tools that allow the study of both the transcriptional processes and the functional complexes underpinning their regulation, in this pathogen. In this project, we will pursue the following aims:    

  1. Devise an in vivo protein labelling technique, suited for the identification of functional protein complexes during infection  
  2. Identify partners of candidate transcriptional regulators, important for virulence  
  3. Validate and characterise protein complexes, required for infection of plants.   

During this project, the researcher will be trained in microbiology, protein chemistry, molecular biology as well as proteomics. Particular attention will be paid to the professional development of researchers on this project by providing career support and active mentoring.

Please see our website for further details on the programme:

Life Sciences MSc by Research MSc by Research (Postgraduate) : Study : University of Dundee

Please note before submitting your application that you must list your top three project choices in the Research Proposal section of the application form.

You apply for this course using our Direct Application System. Once you’ve signed up for an account you’ll be asked to search for a course.

To find Life Science MSc by Research you should select the following options:

·  Course type: Research Postgraduate

·  Keyword: Life

When you complete your form, you should include your top 3 project choices, 2 letters of reference, uploaded under “Other Information” > “Supporting documents” and a personal statement. Failure to do so will delay your application.

Please note when submitting an application that we have the following deadline dates throughout the year:

September Starts – Application Deadline 1st May, Interview Date – Late June

January Starts – Application Deadline 1st Sep, Interview Date – Late October

May Starts – Application Deadline 1st Feb, Interview Date – Late March 

To help us track our recruitment effort, please indicate in your email – cover/motivation letter where ( you saw this posting.

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