PhD in Chemistry: Developing innovative organofluorine chemistry

PhD in Chemistry – Developing innovative organofluorine chemistry

Dr Matthew Tredwell is looking for a PhD student to develop innovative organofluorine chemistry.

Research in the Tredwell group focusses on the development of novel methods for the selective introduction of fluorine and fluorinated group into small molecules. A major theme is the translation of these methods to fluorine-18 radiochemistry to produce diagnostic PET imaging agents for clinical use. For an overview of research in the Tredwell group see (https://profiles.cardiff.ac.uk/staff/tredwellm).

The importance of organofluorine chemistry is highlighted by its presence in 20% of marketed pharmaceuticals and 50% of agrochemicals. The cyclotron-produced positron emitting radionuclide fluorine-18 is ideally suited to applications in medical imaging and the commonly used radionuclide in PET imaging studies. Methods that allow for the selective and efficient synthesis of fluorinated compounds have the potential to have a major impact in these fields. A highly motivated student undertaking this PhD would gain valuable experience in organic synthesis, radiochemistry, automation and radiotracer development/translation throughout the project.

Recent publications from the group in this area include: Nature, 2022, 66, 102; EJNMMI Radiopharmacy and Chemistry 2022, 7, 5; Angew. Chem. Int. Ed. 2019, 58, 472; Angew. Chem. Int. 2017, 56, 11981.

Academic criteria

We require applicants to have a 2.2 BSc or equivalent to be considered for PhD study. Applications are particularly welcome from students with experience in organic synthesis and/or organometallic chemistry.

If English if not your first language then you must fulfil our English Language criteria before the start of your studies. Details of accepted English Language qualifications for admissions can be found here: https://www.cardiff.ac.uk/study/international/english-language-requirements/postgraduate

How to apply

To apply please complete the online application https://www.cardiff.ac.uk/study/postgraduate/research/programmes/programme/chemistry and state the project title and supervisor name

Contact for further information

Please contact Dr Matthew Tredwell (Email: tredwellm@cardiff.ac.uk) for further information. Interested applicants should provide details of their qualifications, including a CV and a brief covering letter outlining their motivation and experience for the position. A formal application must also be submitted.

Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive environment for all. We welcome applications from all members of the global community irrespective of age, disability, sex, gender identity, gender reassignment, marital or civil partnership status, pregnancy or maternity, race, religion or belief and sexual orientation.

We have a range of academics in the School of Chemistry, Cardiff University accepting applications from self-funded PhD students. A list of all our currently available research projects can be found here – PhD project themes – School of Chemistry – Cardiff University