Postdoc (all genders) on microbiota-host interaction incancer

Postdoc (all genders) on microbiota-host interaction in cancer Full time/ Part time  nearmejobs.eu Temporary nearmejobs.eu Arbeitsort: Hamburg Eppendorf

UKE_Zentrum für Onkologie

 

Better together. For life.

At the University Medical Center Hamburg-Eppendorf (UKE), we are committed to excellence in research, education, and comprehensive healthcare across our clinics. Every day, our team of approximately 15,300 dedicated employees works to make the world a healthier place. Our goal is to be one of the leading university hospitals while also being the best employer in our industry.

At UKE, we believe that meaningful and successful work should align with our employees’ personal needs and individual lifestyles. Just as diverse as these needs are, so too is the variety of personalized solutions we offer.

Welcome to the UKE.

  Main tasks

The microbiota comprises the collection of microorganisms inhabiting specific locations, such as the human intestine. It is shaped by environmental influences and nurtured by diet. Certain microbiota profiles are strongly associated with cancer and the outcomes of cancer therapies. But how do they impact the host?

We hypothesize that the microbiota influence the host by degrading dietary components to produce metabolites, which may act locally in the gut or reach distant cancer sites through circulation. Recently, we discovered that a specific microbiota-derived metabolite can modulate the response to chemotherapy in pancreatic cancer models (Tintelnot et al., Nature, 2023).

We are seeking a motivated and innovative candidate with a passion for science and the curiosity to think outside the box. Your goal will be to advance our understanding of microbiota-host interactions in the context of cancer. Your expertise will be key to uncovering the molecular mechanisms behind microbiota-mediated effects on cancer and therapy resistance.

This position is temporary for three years, with the possibility of extension.

Your Profile

• Completed academic studies in chemistry, biology, biochemistry, human biology or related subjects
• Profound knowledge in operating and establishing new methods on a LC/MS
• Profound knowledge in either chemistry (drug design, chemichal modification of metabolites), clinical immunology, microbiota, cancer biology or cancer metabolism
• Prior knowledge in bioinformatic analysis of multi-omic data and/or work with laboratory mice is preferred
• High degree of intrinsic motivation

Our Offer

• Attractive compensation according to TVöD/VKA
• Secure employment with meaningful work and respectful collaboration
• Comprehensive onboarding and open knowledge exchange within the team
• Extensive training and further education programs at our UKE Academy for Education and Careers
• Opportunities to contribute to our “UKE INside” personnel policy through cross-professional and cross-hierarchical projects
• Sustainable travel: subsidies for the Deutschlandticket as a job ticket, and Dr. Bike bicycle service
• Family-friendly working environment: cooperation on childcare, free vacation childcare, advice for employees with relatives in need of care
• Excellent health, wellness, and sports programs
• A wide range of dining options in our staff restaurant, with additional choices available at the “Health Kitchen” cafés, bistros, and an on-site supermarket
• Access to cutting-edge technologies and equipment
• Full-time access to state-of-the-art LC/MS equipment
• Weekly one-on-one meetings with the PI to ensure guidance and progress
• Access to human material for translational studies and a range of sophisticated mouse models (germ-free mice, cancer models, immune cell reporter mice), as well as advanced multi-omics platforms (single-cell sequencing, metabolomic screening, shotgun metagenomics) and corresponding bioinformatics pipelines
• Daily scientific exchange through lab meetings, topic meetings, and journal clubs
• A strong national and international collaboration network
• A dynamic, interdisciplinary team of scientists from diverse fields including medicine, biology, microbiology, and physiology

Contact

We look forward to receiving your complete appli­cation by 14^th March 2025.

APPLY NOW >

Contact to the department
Dr. Joseph Tintelnot
j.tintelnot@uke.de

 

Recruiting contact
Recruiting Team
+49 (0) 40 7410-52599

 

Please note that employment is contingent upon proof of immunization or immunity against the measles virus, in accordance with applicable legal and medical requirements. Documentation (e.g., vaccination certificate) must be provided before employment begins.
 

We live diversity and value variety

We offer a work environment that provides equal opportunities regardless of age, gender, sexual identity, disability, ethnic and social origin, or religion. This is confirmed by our accession to the Charter of Diversity. We explicitly aim to increase the proportion of women in management positions, especially among scientific personnel in research and teaching. Women with equal qualifications will be given priority. The same applies in the case of under-representation of one gender in the advertised area. Persons with severe disabilities with equal aptitude, competence, and professional performance will be given priority.
 

• Learn more about “Diversity at UKE” here