Postdoctoral Fellow in Biochemistry and Molecular Biology

Job title:

Postdoctoral Fellow in Biochemistry and Molecular Biology

Company

Indiana University

Job description

Position DetailsTitle Postdoctoral Fellow in Biochemistry and Molecular Biology
Specific Title
Appointment Type Postdoctoral Fellow
Department IUSM – Biochemistry & Molecular Biology
Campus IU School of Medicine Indianapolis
Position SummaryWe are seeking candidates for a postdoctoral position in the laboratory of Dr. Jaeyeon Kim, an associate professor, in the Department of Biochemistry and Molecular Biology at Indiana University School of Medicine (IUSM-Indianapolis) and IU Simon Comprehensive Cancer Center.Dr. Kim studies the molecular mechanisms underlying the development and progression of ovarian and breast cancer with genetically engineered mouse models and human specimens. The current research focus is to elucidate a conundrum surrounding high cancer risks and distinct cancer susceptibility among BRCA1 carriers. Despite the fact that every cell in their body has a harmful BRCA1 mutation, these women are predisposed particularly to ovarian and breast cancers. It remains a mystery. A seminal study (PNAS 2020; PMID: 33262282) from his lab points to the ovarian hormone progesterone as the culprit for BRCA1 carriers’ distinctive susceptibility to ovarian and breast cancer. Integrating this novel insight and unique Brca1 mouse models, his lab is seeking to decipher the molecular mechanisms underlying the progesterone regulation of ovarian and breast cancer development in BRCA1 carriers-with an emphasis on DNA damage/repair, cell-cycle checkpoint regulation, and immune modulation. This innovative, high-impact research will not only reveal a basic molecular mechanism of cancer susceptibility with BRCA1 mutations, but this knowledge will also offer an innovative strategy for the effective nonsurgical prevention and control of these formidable cancers wreaking havoc on women.IUSM is committed to being an institution that reflects the learners we teach and the patient populations we serve and pursues the values of equity and inclusion that inform academic excellence. We desire candidates whose work contributes to equitable and inclusive learning and working environments for our learners, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.
Basic QualificationsResearch experience with mice or mouse models-accompanied by molecular biology skills, including PCR, QPCR, western blot, cloning, cell culture, and immunohistochemistry-would be desirable, though not required. Candidates for the postdoctoral position should have, or are expected to receive, a doctoral degree (Ph.D.) in biological or biomedical sciences. Also anticipated are motivation and commitment to research and science with the ability to work independently. The laboratory will offer an interactive, intellectually stimulating yet relaxed research and academic environment. Also, the PI will help promote the career development of researchers in the laboratory. As part of these efforts, besides research training, mentoring and training will also be offered in learning how to write and present their research and science effectively.
Department Contact for QuestionsIf you are interested in participating in this research program of ovarian and breast cancer, please send (in pdf) CV (including eligibility, detailed research experience, and names of three references) to Dr. Jaeyeon Kim at
Additional Qualifications
Special Instructions
Priority Application Review Deadline
Expected Start Date 05/01/2024
OAA # IUSM-01945-2024

Expected salary

Location

Indianapolis, IN

Job date

Sun, 30 Jun 2024 06:44:33 GMT

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